Recombinant Hirudin protein (Active) (ab201396)
Key features and details
- Expression system: Saccharomyces cerevisiae
- Purity: > 96% SDS-PAGE
- Endotoxin level:
- Active: Yes
- Suitable for: Functional Studies, HPLC, SDS-PAGE
Preparation and Storage
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Alternative names
- Hirudin 1
- Lepirudin
- Refludan
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Relevance
Hirudin is a highly effective and very specific anticoagulant which specifically inhibits formation of fibrin and activation of factors V, VIII and XIII by forming irreversible, noncovalent 1:1 complexes with a-thrombin. Hirudin is a 65 amino acid polypeptide, 7 kDa protein naturally originating from the medical leech Hirudo medicinalis. It is the most potent thrombin inhibitor known to date. -
Cellular localization
Secreted
