Raloxifene hydrochloride, estrogen receptor modulator (SERM) (ab141959)
Key features and details
- Selective estrogen receptor modulator (SERM)
- CAS Number: 82640-04-8
- Purity: > 98%
- Soluble in DMSO 50 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Raloxifene hydrochloride, estrogen receptor modulator (SERM) -
Description
Selective estrogen receptor modulator (SERM) -
Biological description
Selective estrogen receptor modulator (SERM). Binds to both ERα (Kd = 90pM) and ERβ. Tissue-dependently inhibits or activates ER-induced transcription. Inhibits estradiol-induced progesterone receptor activity in hypothalamic cells (IC50 = 1nM). Orally Active. -
Purity
> 98% -
CAS Number
82640-04-8 -
Chemical structure
Properties
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Chemical name
[6-Hydroxy-2-(4-hydroxyphenyl)-1-benzothiophen-3-yl]-[4-(2-piperidin-1-ylethoxy)phenyl]methanone hydrochloride -
Molecular weight
510.05 -
Molecular formula
C28H27NO4S.HCl -
PubChem identifier
54900 -
Storage instructions
Store at Room Temperature. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO 50 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
C1CCN(CC1)CCOC2=CC=C(C=C2)C(=O)C3=C(SC4=C3C=CC(=C4)O)C5=CC=C(C=C5)O.Cl -
Source
Synthetic
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Research areas
