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Biochemicals Product Range Just Add Water

(R)-Sulforaphane, Ah receptor antagonist (ab141971)

Key features and details

  • Non-competitive antagonist of the Ah receptor
  • CAS Number: 142825-10-3
  • Purity: > 98%
  • Soluble in DMSO, ethanol or water
  • Form / State: Solid
  • Source: Brassica oleracea

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Overview

  • Product name

    (R)-Sulforaphane, Ah receptor antagonist
  • Description

    Non-competitive antagonist of the Ah receptor
  • Biological description

    Non-competitive antagonist of the aryl hydrocarbon receptor. Natural isothiocyanate. Antioxidant, promotes cell proliferation, reduces senescence and apoptosis. Upregulates CYP1A1/1B1 apoprotein levels in vivo. Chemopreventive. S-Sulforaphane (ab141970) and R,S-Sulforaphane (ab141969) also available.
  • Purity

    > 98%
  • General notes

    ab141971 is a neat liquid at room temperature. It is not dissolved in solvent. We measure this material by weight, not by volume. In small quantities (Solubility - ethanol, DMSO, methanol, ethyl acetate, and water.

    Ampoule Instructions:
    1. For your protection, wear safety gloves and other appropriate safety equipment.
    2. Inspect the ampoule to ensure it isn’t broken. If it is broken, please contact us for a replacement.
    3. Wrap a towel around the ampoule to shield yourself from glass shards.
    4. Using both hands, gently snap the ampoule along the pre-scored line. Be careful not to splash the compound out of the ampoule.
    5. Wash both the top and bottom parts of the ampoule out with solvent to ensure you get all of the material out of the ampoule.

  • CAS Number

    142825-10-3
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    1-Isothiocyanato-4-[(R)-methylsulfinyl]butane
  • Molecular weight

    177.29
  • Molecular formula

    C6H11NOS2
  • PubChem identifier

    9577379
  • Storage instructions

    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in DMSO, ethanol or water
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    C[S@@](=O)CCCCN=C=S
  • Source

    Brassica oleracea

  • Research areas

    • Biochemicals
    • Product Range
    • Just Add Water
    • Biochemicals
    • Chemical Type
    • Biochemicals
    • Biochemicals
    • Pharmacology
    • Signaling
    • Apoptosis & cell cycle
    • Other
    • Biochemicals
    • Pharmacology
    • Receptors & Transporters
    • Nuclear Receptors
    • Aryl hydrocarbon receptors
    • Biochemicals
    • Pharmacology
    • Signaling
    • DNA, RNA & protein synthesis
    • General

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