R-(+)-DIOA (R(+)-Butylindazone), K+/Cl--cotransporter inhibitor (ab145200)
Key features and details
- Selective K+/Cl--cotransporter inhibitor
- CAS Number: 81166-47-4
- Purity: > 98%
- Soluble in ethanol and in DMSO to 50 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
R-(+)-DIOA (R(+)-Butylindazone), K+/Cl--cotransporter inhibitor -
Description
Selective K+/Cl--cotransporter inhibitor -
Biological description
Selective K+/Cl--cotransporter inhibitor. Does not affect the bumetanide-sensitive Na+/K+/Cl--cotransport system. Suppresses osteoclastic pit formation and Cl- and H+ extrusion. -
Purity
> 98% -
CAS Number
81166-47-4 -
Chemical structure
Properties
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Chemical name
2-[[(2S)-2-Butyl-6,7-dichloro-2-cyclopentyl-1-oxo-3H-inden-5-yl]oxy]acetic acid -
Molecular weight
399.31 -
Molecular formula
C20H24Cl2O4 -
PubChem identifier
10386195 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in ethanol and in DMSO to 50 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CCCC[C@]1(CC2=CC(=C(C(=C2C1=O)Cl)Cl)OCC(=O)O)C3CCCC3 -
Source
Synthetic
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Research areas
