Pyrintegrin, enhances hESC survival (ab142093)
Key features and details
- Pyrimidine compound that enhances hESC survival
- CAS Number:
- Purity: > 95%
- Soluble in DMSO
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Pyrintegrin, enhances hESC survival -
Description
Pyrimidine compound that enhances hESC survival -
Alternative names
- Ptn
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Biological description
Pyrimidine compound that enhances hESC survival. Substantially reduces trypsinization-induced apoptosis while maintaining cells’ self-renewal ability and pluripotency of expanded cultures. Induces activation of β1 integrin and multiple growth factor receptors, including FGFR1, IGFR1, EGFR1, and ErbB2. Active in vitro. -
Purity
> 95% -
Chemical structure
Properties
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Chemical name
N-(Cyclopropylmethyl)-4-(4-(6-hydroxy-3,4-dihydroquinolin-1-(2H)-yl)pyrimidin-2-ylamino)benzenesulfonamide -
Molecular weight
451.54 -
Molecular formula
C23H25N5O3S -
PubChem identifier
46223724 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
C1CC2=C(C=CC(=C2)O)N(C1)C3=NC(=NC=C3)NC4=CC=C(C=C4)S(=O)(=O)NCC5CC5 -
Source
Synthetic