Pterostilbene, Antioxidant and antiapoptotic agent (ab120961)
Key features and details
- Antioxidant and antiapoptotic agent; analog of resveratrol
- CAS Number: 537-42-8
- Purity: > 98%
- Soluble in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Pterostilbene, Antioxidant and antiapoptotic agent -
Description
Antioxidant and antiapoptotic agent; analog of resveratrol -
Biological description
Antioxidant and antiapoptotic agent; analog of resveratrol (ab120726). Antineoplastic properties in vitro and in vivo.
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Purity
> 98% -
CAS Number
537-42-8 -
Chemical structure
Properties
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Chemical name
4-[(1E)-2-(3,5-Dimethoxyphenyl)ethenyl]phenol -
Molecular weight
256.30 -
Molecular formula
C16H16O3 -
Storage instructions
Store at -20°C. Store In the Dark. Store under desiccating conditions. This product is air and light sensitive and impurities can occur as a result of air oxidation or due to metabolism by microbes. -
Solubility overview
Soluble in DMSO to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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Source
Synthetic
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Research areas
Images
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Functional Studies - Pterostilbene, Antioxidant and antiapoptotic agent (ab120961)ab51031 staining beclin1 in MCF7 cells treated with pterostilbene (ab120961), by ICC/IF. Increase in beclin1 expression correlates with increased concentration of pterostilbene as described in literature.
The cells were incubated at 37°C for 48h in media containing different concentrations of ab120961 (pterostilbene) in DMSO, fixed with 4% formaldehyde for 10 minutes at room temperature and blocked with PBS containing 10% goat serum, 0.3 M glycine, 1% BSA and 0.1% tween for 2h at room temperature. Staining of the treated cells with ab51031 (5 µg/ml) was performed overnight at 4°C in PBS containing 1% BSA and 0.1% tween. A DyLight 488 goat anti-rabbit polyclonal antibody (ab96899) at 1/250 dilution was used as the secondary antibody.
