Propafenone hydrochloride, Na+, Ca2+ and K+ channel blocker (ab142357)
Key features and details
- Na+, Ca2+ and K+ channel blocker
- CAS Number: 34183-22-7
- Purity: > 98%
- Soluble in ethanol and in water (with warming)
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Propafenone hydrochloride, Na+, Ca2+ and K+ channel blocker -
Description
Na+, Ca2+ and K+ channel blocker -
Biological description
Na+, Ca2+ and K+ channel blocker. Suppresses atrial fibrillation in vivo. Blocks ATP-sensitive K+ channels reversibly and voltage-independently (EC50 values are 1 and 5 μM for atrial and ventricular myocytes, respectively). Orally active. -
Purity
> 98% -
CAS Number
34183-22-7 -
Chemical structure
Properties
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Chemical name
1-[2-[2-Hydroxy-3-(propylamino)propoxy]phenyl]-3-phenylpropan-1-one hydrochloride -
Molecular weight
377.91 -
Molecular formula
C21H27NO3.HCl -
PubChem identifier
36708 -
Storage instructions
Store at Room Temperature. The product can be stored for up to 12 months. -
Solubility overview
Soluble in ethanol and in water (with warming) -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CCCNCC(COC1=CC=CC=C1C(=O)CCC2=CC=CC=C2)O.Cl -
Source
Synthetic
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Research areas
