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Biochemicals

Pitstop® 2 - negative control, Negative control for clathrin inhibitor Pitstop® 2 (ab120688)

Price and availability

150 768 ₸

Availability

Order now and get it on Thursday February 25, 2021

Key features and details

  • Negative control for clathrin inhibitor Pitstop® 2 (ab120687)
  • Purity: > 99%
  • Soluble in DMSO
  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    Pitstop® 2 - negative control, Negative control for clathrin inhibitor Pitstop® 2
  • Description

    Negative control for clathrin inhibitor Pitstop® 2 (ab120687)
  • Biological description

    Negative control for clathrin inhibitor Pitstop® 2 (ab120687) which is of the same chemical class and has a highly related structure to Pitstop® 2. Inhibits amphiphysin binding to the clathrin TD with an IC50 >100 μM and does not block receptor-mediated endocytosis at concentrations of up to 300 μM (unpublished reports).

  • Purity

    > 99%
  • General notes

    Sold under exclusive licence from Children's Medical Research Institute and Newcastle Innovation Ltd. Pitstop® is a trademark of Freie Universitat Berlin, Newcastle Innovation Ltd. and Children's Medical Research Institute
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    5-(4-Bromobenzylidene)-2-(naphthalen-1-ylamino)-1,3-thiazol-4(5H)-one
  • Molecular weight

    409.30
  • Molecular formula

    C20H13BrN2OS
  • Storage instructions

    Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in DMSO
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • Source

    Synthetic

  • Research areas

    • Biochemicals
    • Chemical Type
    • Biochemicals
    • Biochemicals
    • Pharmacology
    • Signaling
    • Endocytosis & exocytosis
    • Clathrin
    • Biochemicals
    • Research Area
    • Heart disease
    • Signaling
    • Endocytosis & exocytosis
    • Clathrin
    • Biochemicals
    • Research Area
    • Pain & inflammation
    • Signaling
    • Endocytosis & exocytosis
    • Clathrin
    • Biochemicals
    • Research Area
    • Alzheimer's Disease
    • Signaling
    • Endocytosis & exocytosis
    • Clathrin
    • Biochemicals
    • Research Area
    • Diabetes
    • Signaling
    • Endocytosis & exocytosis
    • Clathrin
    • Biochemicals
    • Research Area
    • Hypertension
    • Signaling
    • Endocytosis & exocytosis
    • Clathrin
    • Biochemicals
    • Research Area
    • Obesity
    • Signaling
    • Endocytosis & exocytosis
    • Clathrin
    • Biochemicals
    • Research Area
    • Respiratory disease
    • Signaling
    • Endocytosis & exocytosis
    • Clathrin
    • Biochemicals
    • Research Area
    • Stroke
    • Signaling
    • Endocytosis & exocytosis
    • Clathrin

Images

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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