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Phloretin, Dihydrochalcones flavonoid (ab143143)

Price and availability

77 059 ₸

Availability

Order now and get it on Thursday March 04, 2021

Key features and details

  • Dihydrochalcones flavonoid
  • CAS Number: 60-82-2
  • Purity: > 99%
  • Soluble in DMSO to 100 mM and in ethanol to 25 mM
  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    Phloretin, Dihydrochalcones flavonoid
  • Description

    Dihydrochalcones flavonoid
  • Biological description

    Dihydrochalcones flavonoid. GLUT inhibitor. Active phlorizin (ab143144) metabolite. Blocks L-type Ca2+ channels. Activates Ca2+ -activated K+ channels. Inhibits platelet aggregation. Induces apoptosis. Shows antitumor effects in vivo. Orally active.
  • Purity

    > 99%
  • CAS Number

    60-82-2
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    3-(4-Hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)propan-1-one
  • Molecular weight

    274.27
  • Molecular formula

    C15H14O5
  • PubChem identifier

    4788
  • Storage instructions

    Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in DMSO to 100 mM and in ethanol to 25 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    C1(=CC(=C(C(=C1)O)C(CCC2=CC=C(C=C2)O)=O)O)O
  • Source

    Synthetic

  • Research areas

    • Cardiovascular
    • Lipids / Lipoproteins
    • Lipid Metabolism
    • Cytochromes
    • Epigenetics and Nuclear Signaling
    • Transcription
    • Domain Families
    • Zinc Finger
    • Signal Transduction
    • Signaling Pathway
    • Nuclear Signaling
    • Nuclear Hormone Receptors
    • Estrogen
    • Signal Transduction
    • Growth Factors/Hormones
    • FGF
    • Neuroscience
    • Endocrine system
    • Gonadotrophic axis
    • Epigenetics and Nuclear Signaling
    • Nuclear Signaling Pathways
    • Nuclear Receptors
    • Estrogen
    • Signal Transduction
    • Metabolism
    • Drug metabolism
    • Cancer
    • Signal transduction
    • Nuclear signaling
    • Nuclear hormone receptors
    • Estrogen
    • Cancer
    • Tumor biomarkers
    • Receptors
    • Biochemicals
    • Product Range
    • New
    • Biochemicals
    • Chemical Type
    • Biochemicals
    • Metabolism
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    • Metabolic signaling pathways
    • Lipid and lipoprotein metabolism
    • Lipases
    • Metabolism
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    • Metabolic signaling pathways
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    • Pathways and Processes
    • Mitochondrial Metabolism
    • Cytochromes
    • Biochemicals
    • Pharmacology
    • Signaling
    • Immunomodulators
    • Immunomodulators & Immunosuppressants

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