PD318088, MEK1/2. inhibitor (ab235566)
Key features and details
- Small molecule, allosteric, non-ATP-competitive inhibitor of MEK1/2.
- CAS Number: 391210-00-7
- Purity: > 98%
DMSO 112 mg/mL (199.61 mM)
Ethanol 14 mg/mL (24.95 mM)
Insoluble in water
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
PD318088, MEK1/2. inhibitor -
Description
Small molecule, allosteric, non-ATP-competitive inhibitor of MEK1/2. -
Purity
> 98% -
CAS Number
391210-00-7 -
Chemical structure
Properties
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Chemical name
5-bromo-N-(2,3-dihydroxypropoxy)-3,4-difluoro-2-(2-fluoro-4-iodoanilino)benzamide
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Molecular weight
561.09 -
Molecular formula
C16H13BrF3IN2O4 -
PubChem identifier
10231331 -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. It is important to note that this is air sensitive and impurities can occur as a result of air oxidation. Store In the Dark. Store under desiccating conditions. -
Solubility overview
DMSO 112 mg/mL (199.61 mM)
Ethanol 14 mg/mL (24.95 mM)
Insoluble in water
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Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
C1=CC(=C(C=C1I)F)NC2=C(C(=C(C=C2C(=O)NOCC(CO)O)Br)F)F -
Source
Synthetic