OSMI-1, O-GlcNAc transferase (OGT) inhibitor (ab235455)
Key features and details
- Potent, cell-permeable, O-GlcNAc transferase (OGT) inhibitor.
- CAS Number: 1681056-61-0
- Purity: > 98%
DMSO ~20 mg/mL
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
OSMI-1, O-GlcNAc transferase (OGT) inhibitor -
Description
Potent, cell-permeable, O-GlcNAc transferase (OGT) inhibitor. -
Biological description
Potent, cell-permeable, O-GlcNAc transferase (OGT) inhibitor. Inhibits protein O-GlcNAcylation in several mammalian cell lines without qualitatively altering cell surface N- or O-linked glycans.
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Purity
> 98% -
CAS Number
1681056-61-0 -
Chemical structure
Properties
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Chemical name
αR-α-[[(1,2-Dihydro-2-oxo-6-quinolinyl)sulfonyl]amino]-N-(2-furanylmethyl)-2-methoxy-N-(2-thienylmethyl)-benzeneacetamide
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Molecular weight
563.64 -
Molecular formula
C28H25N3O6S2 -
PubChem identifier
118634407 -
Storage instructions
Shipped at Room Temperature. Store at -20°C. Store In the Dark. Store under desiccating conditions. -
Solubility overview
DMSO ~20 mg/mL
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Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
COC1=CC=CC=C1C(C(=O)N(CC2=CC=CO2)CC3=CC=CS3)NS(=O)(=O)C4=CC5=C(C=C4)NC(=O)C=C5 -
Source
Synthetic