OM173-alphaA, DNMT3B and FTase inhibitor (ab144849)
Key features and details
- DNMT3B and FTase inhibitor. Antibiotic and antimycoplasmal agent.
- CAS Number: 58286-56-9
- Purity: > 95%
- Soluble in DMSO and in ethanol
- Form / State: Solid
- Source: Streptomyces sp.
Overview
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Product name
OM173-alphaA, DNMT3B and FTase inhibitor -
Description
DNMT3B and FTase inhibitor. Antibiotic and antimycoplasmal agent. -
Biological description
Potent, selective DNA (cytosine-5)-methyltransferase 3B (DNMT3B) inhibitor (IC50 = 500nM). Farnesyltransferase (FTase) inhibitor (IC50 = 3.2μM). Antibiotic and antimycoplasmal agent. Nanaomycin A methyl ester. -
Purity
> 95% -
CAS Number
58286-56-9 -
Chemical structure
Properties
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Chemical name
Methyl 2-[(1S,3R)-9-hydroxy-1-methyl-5,10-dioxo-3,4-dihydro-1H-benzo[g]isochromen-3-yl]acetate -
Molecular weight
316.31 -
Molecular formula
C17H16O6 -
PubChem identifier
12803368 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO and in ethanol -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
C[C@H]1C2=C(C[C@@H](O1)CC(=O)OC)C(=O)C3=C(C2=O)C(=CC=C3)O -
Source
Streptomyces sp.
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Research areas
