O-1918, non-CB1 vascular cannabinoid receptor antagonist (ab120405)
Key features and details
- Antagonist of the non-CB1 vascular cannabinoid receptor
- CAS Number: 536697-79-7
- Purity: > 97%
- Soluble in DMSO to 100 mM and in ethanol to 100 mM
- Form / State: Liquid
- Source: Synthetic
Overview
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Product name
O-1918, non-CB1 vascular cannabinoid receptor antagonist -
Description
Antagonist of the non-CB1 vascular cannabinoid receptor -
Biological description
Silent antagonist of the non-CB1 vascular cannabinoid receptor (the 'Abn-CBD' receptor recently reported to be GPR18). Cannabidiol antagonist. Blocks Abn-CBD induced potentiation of a Ca2+-activated K+ current in human umbilical vein endothelial cells.
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Purity
> 97% -
General notes
To change the solvent, simpley evaporate the mythyl acetate under a gentle stream of nitrogen and immediately add the solvent of choice.
Sold under license from Virginia Commonwealth University.
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CAS Number
536697-79-7 -
Chemical structure
Properties
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Chemical name
1,3-Dimethoxy-5-methyl-2-[(1R,6R)-3-methyl-6-(1-methylethenyl)-2-cyclohexen-1-yl]benzene -
Molecular weight
286.41 -
Molecular formula
C19H26O2 -
PubChem identifier
40469923 -
Storage instructions
Store at -20°C. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 100 mM and in ethanol to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC(=C)[C@@H]2CCC(C)=C[C@H]2c1c(OC)cc(C)cc1OC -
Source
Synthetic
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Research areas