NSC-687852, USP14 and UCHL5 inhibitor (ab142195)
Key features and details
- Cell-permeable USP14 and UCHL5 inhibitor. Apoptotic agent.
- CAS Number:
- Purity: > 98%
- Soluble in DMSO to 75 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
NSC-687852, USP14 and UCHL5 inhibitor -
Description
Cell-permeable USP14 and UCHL5 inhibitor. Apoptotic agent. -
Alternative names
- b-AP15
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Biological description
Cell-permeable USP14 and UCHL5 inhibitor. Apoptotic agent. Induces mitochondrial apoptosis via cathepsin D-dependent caspase-cleavage. Shows antitumor effects in vivo. -
Purity
> 98% -
Chemical structure
Properties
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Chemical name
(3E,5E)-3,5-Bis[(4-nitrophenyl)methylidene]-1-prop-2-enoylpiperidin-4-one -
Molecular weight
419.39 -
Molecular formula
C22H17N3O6 -
PubChem identifier
5351435 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 75 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
C=CC(=O)N1CC(=CC2=CC=C(C=C2)[N+](=O)[O])C(=O)C(=CC3=CC=C(C=C3)[N+](=O)[O-])C1 -
Source
Synthetic
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Research areas
