ab213658 is a Non Homologous End Joining Panel designed for the detection and characterization of key proteins involved in DNA double strand break (DSB) repair by non-homologous end joining (NHEJ). Histone H2A.X is phosphorylated on S139, termed gamma H2A.X, at sites of DNA damage. DNA DSB repair by NHEJ requires Ku70/Ku80 heterodimer binding to the DSB, as well as DNA Ligase IV for ligation of DNA ends.

This panel contains 5 recombinant rabbit monoclonal antibodies. They are provided as a sampler panel to allow you to easily evaluate each in your applications.

The panel contains: 

- Rabbit monoclonal anti-Histone H2A.X antibody [EPR895] - ChIP Grade (ab124781)

- Rabbit monoclonal anti-gamma H2A.X (phospho S139) antibody [EP854(2)Y] - ChIP Grade (ab81299) 

- Rabbit monoclonal anti-DNA Ligase IV/LIG4 antibody [EPR16531] (ab193353)

- Rabbit monoclonal anti-Ku70 antibody [EPR4027] (ab92450)

- Rabbit monoclonal anti-Ku80 antibody [EPR3468] (ab80592)

For guidelines on how to use each antibody within the panel, please consult the individual datasheet for each antibody.

• Epigenetics and Nuclear Signaling
• Histones
• Variants

• Epigenetics and Nuclear Signaling
• DNA / RNA
• DNA Damage & Repair
• Non Homol. End Joining

• Epigenetics and Nuclear Signaling
• DNA / RNA
• DNA Damage & Repair
• DNA Damage Response
• DNA Damage Recognition

• Epigenetics and Nuclear Signaling
• DNA / RNA
• DNA Synthesis
• DNA Ligases

• Epigenetics and Nuclear Signaling
• Histones
• H2A
• Unmodified

• Epigenetics and Nuclear Signaling
• Histones
• H2A
• Variants

• Cancer
• Cell cycle
• Cell division

• Epigenetics and Nuclear Signaling
• Epigenetics and Nuclear Signaling Antibody Panels
• DNA Damage Antibody Panels