Nicardipine, L-type Ca2+ channel blocker (ab142923)
Key features and details
- Potent L-type Ca2+ channel blocker
- CAS Number: 55985-32-5
- Purity: > 98%
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Nicardipine, L-type Ca2+ channel blocker -
Description
Potent L-type Ca2+ channel blocker -
Biological description
Potent L-type Ca2+ channel blocker. Alters cytochrome P-450 3A (CYP3A4) expression in rat livers. Elastase inhibitor (IC50= 16μM in humans and 18μM in rat). Active in vivo and in vitro. -
Purity
> 98% -
CAS Number
55985-32-5 -
Chemical structure
Properties
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Chemical name
5-O-[2-[Benzyl(methyl)amino]ethyl] 3-O-methyl-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate -
Molecular weight
479.52 -
Molecular formula
C26H29N3O6 -
PubChem identifier
4474 -
Storage instructions
Store at Room Temperature. The product can be stored for up to 12 months. -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC1=C(C(C(=C(N1)C)C(=O)OCCN(C)CC2=CC=CC=C2)C3=CC(=CC=C3)[N+](=O)[O-])C(=O)OC -
Source
Synthetic
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Research areas
- Metabolism
- Pathways and Processes
- Metabolic signaling pathways
- Lipid and lipoprotein metabolism
- Lipases
- Metabolism
- Pathways and Processes
- Metabolic signaling pathways
- Lipid and lipoprotein metabolism
- Fatty acids
