Mouse I-TAC ELISA Kit (CXCL11) (ab100716)
Key features and details
- Sensitivity: 6 pg/ml
- Range: 5.487 pg/ml - 4000 pg/ml
- Sample type: Cell culture supernatant, Plasma, Serum
- Detection method: Colorimetric
- Assay type: Sandwich (quantitative)
- Reacts with: Mouse
Properties
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Storage instructions
Store at -20°C. Please refer to protocols. -
Components 1 x 96 tests 20X Wash Buffer Concentrate 1 x 25ml 300X HRP-Streptavidin Concentrate 1 x 200µl 5X Assay Diluent B 1 x 15ml Assay Diluent A 1 x 30ml Biotinylated anti-mouse I-TAC (lyophilized) 2 vials I-TAC Microplate (12 x 8 wells) 1 unit Recombinant mouse I-TAC Standard (lyophilized) 2 vials Stop Solution 1 x 8ml TMB One-Step Substrate Reagent 1 x 12ml -
Research areas
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Function
Chemotactic for interleukin-activated T-cells but not unstimulated T-cells, neutrophils or monocytes. Induces calcium release in activated T-cells. Binds to CXCR3. May play an important role in CNS diseases which involve T-cell recruitment. May play a role in skin immune responses. -
Tissue specificity
High levels in peripheral blood leukocytes, pancreas and liver astrocytes. Moderate levels in thymus, spleen and lung. Low levels in placenta, prostate and small intestine. Also found in epidermal basal layer keratinocytes in skin disorders. -
Sequence similarities
Belongs to the intercrine alpha (chemokine CxC) family. -
Cellular localization
Secreted. - Information by UniProt
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Alternative names
- b R1
- b-R1
- Beta-R1
see all -
Database links
- Entrez Gene: 56066 Mouse
- SwissProt: Q9JHH5 Mouse
- Unigene: 131723 Mouse
Images
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Typical standard curve
Representative standard curve using ab100716
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Typical standard curveRepresentative standard curve using ab100716
