ML-167, Cdc2-like kinase 4 inhibitor (ab146151)
Key features and details
- Potent, highly selective Cdc2-like kinase 4 inhibitor
- CAS Number: 1285702-20-6
- Soluble in ethanol to 25 mM (with warming) and in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
ML-167, Cdc2-like kinase 4 inhibitor -
Description
Potent, highly selective Cdc2-like kinase 4 inhibitor -
Biological description
Potent, highly selective Cdc2-like kinase 4 inhibitor (IC50 = 136 nM). Cell-permeable. Putatively ATP-competitive Clk4 inhibitor. -
CAS Number
1285702-20-6 -
Chemical structure
Properties
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Chemical name
[5-[4-[(5-Methylfuran-2-yl)methylamino]quinazolin-6-yl]furan-2-yl]methanol -
Molecular weight
335.36 -
Molecular formula
C19H17N3O3 -
PubChem identifier
44968231 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in ethanol to 25 mM (with warming) and in DMSO to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC1=CC=C(O1)CNC2=NC=NC3=C2C=C(C=C3)C4=CC=C(O4)CO -
Source
Synthetic
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Research areas