MK886, Lipoxygenase inhibitor (ab141140)
Key features and details
- Potent lipoxygenase inhibitor
- CAS Number: 118414-82-7
- Purity: > 98%
- Soluble in DMSO to 50 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
MK886, Lipoxygenase inhibitor -
Description
Potent lipoxygenase inhibitor -
Biological description
Potent 5-lipoxygenase activating protein inhibitor (FLAP) (IC50 = 44 nM). Inhibits leukotriene biosynthesis (IC50 = 2.5 nM) in vitro and tumor activity in vivo. Displays PPARα antagonist activity. Orally active in vivo.
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Purity
> 98% -
CAS Number
118414-82-7 -
Chemical structure
