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Neuroscience Neurotransmitter Biogenic Amines Dopamine

Mitotane, adrenolytic and antineoplastic agent (ab142724)

Key features and details

  • Potent adrenolytic and antineoplastic agent
  • CAS Number: 53-19-0
  • Purity: > 98%
  • Soluble in DMSO to 100 mM and in ethanol to 100 mM
  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    Mitotane, adrenolytic and antineoplastic agent
  • Description

    Potent adrenolytic and antineoplastic agent
  • Biological description

    Potent adrenolytic and antineoplastic agent. Induces caspase-mediated apoptosis. Reduces cortisol secretion in vivo. Orally active.
  • Purity

    > 98%
  • CAS Number

    53-19-0
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    1-Chloro-2-[2,2-dichloro-1-(4-chlorophenyl)ethyl]benzene
  • Molecular weight

    320.04
  • Molecular formula

    C14H10Cl4
  • PubChem identifier

    4211
  • Storage instructions

    Store at Room Temperature. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in DMSO to 100 mM and in ethanol to 100 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    C1=CC=C(C(=C1)C(C2=CC=C(C=C2)Cl)C(Cl)Cl)Cl
  • Source

    Synthetic

  • Research areas

    • Neuroscience
    • Neurotransmitter
    • Biogenic Amines
    • Dopamine
    • Neuroscience
    • Neurotransmitter
    • Biogenic Amines
    • Serotonin / 5HT
    • Neuroscience
    • Neurotransmitter
    • Transporters
    • Dopamine
    • Neuroscience
    • Neurotransmitter
    • Transporters
    • Other
    • Neuroscience
    • Neurotransmission
    • Receptors / Channels
    • Sodium Channels
    • Neuroscience
    • Neurotransmission
    • Receptors / Channels
    • GPCR
    • Serotonin Receptors
    • Neuroscience
    • Neurotransmitter
    • Transporters
    • Other Transporters
    • Signal Transduction
    • Metabolism
    • Drug metabolism
    • Cardiovascular
    • Atherosclerosis
    • Ischemia / Reperfusion
    • Biochemicals
    • Product Range
    • New
    • Biochemicals
    • Chemical Type
    • Biochemicals
    • Biochemicals
    • Pharmacology
    • Signaling
    • Apoptosis & cell cycle
    • Caspase
    • Biochemicals
    • Pharmacology
    • Receptors & Transporters
    • Adrenoceptors
    • Non-selective
    • Antagonists
    • Metabolism
    • Pathways and Processes
    • Metabolic signaling pathways
    • Drug metabolism
    • Metabolism
    • Types of disease
    • Obesity

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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