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Neuroscience Neurotransmitter Biogenic Amines Dopamine

Ebastine, Histamine H1 receptor antagonist (ab141928)

Key features and details

  • Histamine H1 receptor antagonist
  • CAS Number: 90729-43-4
  • Purity: > 98%
  • Soluble in DMSO to 10 mM
  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    Ebastine, Histamine H1 receptor antagonist
  • Description

    Histamine H1 receptor antagonist
  • Biological description

    Histamine H1 receptor antagonist. Does not penetrate the blood-brain barrier. A CYP2J substrate, metabolized into carebastine via hydroxyebastine in vivo.
  • Purity

    > 98%
  • CAS Number

    90729-43-4
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    4-(4-Benzhydryloxypiperidin-1-yl)-1-(4-tert-butylphenyl)butan-1-one
  • Molecular weight

    469.66
  • Molecular formula

    C32H39NO2
  • PubChem identifier

    3191
  • Storage instructions

    Store at Room Temperature. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in DMSO to 10 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CC(C)(C)C1=CC=C(C=C1)C(=O)CCCN2CCC(CC2)OC(C3=CC=CC=C3)C4=CC=CC=C4
  • Source

    Synthetic

  • Research areas

    • Neuroscience
    • Neurotransmitter
    • Biogenic Amines
    • Dopamine
    • Neuroscience
    • Neurotransmitter
    • Biogenic Amines
    • Serotonin / 5HT
    • Neuroscience
    • Neurotransmitter
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    • Other
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    • Receptors / Channels
    • GPCR
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