Lysophosphatidic acid sodium salt, autophagy inhibitor (ab146430)
Key features and details
- Autophagy inhibitor
- CAS Number: 22556-62-3
- Purity: > 98%
Soluble in water to 20 mM (with warming)
- Form / State: Solid
- Source: Synthetic
Overview
-
Product name
Lysophosphatidic acid sodium salt, autophagy inhibitor -
Description
Autophagy inhibitor -
Alternative names
- 1-O-9Z-octadecenoyl-sn-glyceryl-3-phosphoric acid, sodium salt
- 1-Oleoyl-lysophosphatidic acid sodium salt
- LPA sodium salt
see all -
Biological description
Endogenous agonist of the Lysophosphatidic acid (LPA) receptors. Induces cellular functions such as cell proliferation and migration, and ICAM-1, IL-8 and MCP-1 expression. Inhibits autophagy in cells under starvation conditions by inhibiting autophagosome formation.
-
Purity
> 98% -
CAS Number
22556-62-3 -
Chemical structure
Properties
-
Chemical name
1-O-9Z-Octadecenoyl-sn-glyceryl-3-phosphoric acid sodium salt
-
Molecular weight
458.50 -
Molecular formula
C21H40O7P.Na -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water to 20 mM (with warming)
-
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
-
SMILES
C(O[P](=O)(O)O)C(O)COC(=O)CCCCCCC\C=C/CCCCCCCC -
Source
Synthetic
