Ledipasvir, 5A of hepatitis C virus inhibitor (ab231508)
Key features and details
- Inhibitor of non-structural protein 5A of hepatitis C virus
- CAS Number: 1256388-51-8
Soluble in ethanol to 25 mM and in DMSO to 10mM.
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Ledipasvir, 5A of hepatitis C virus inhibitor -
Description
Inhibitor of non-structural protein 5A of hepatitis C virus -
Alternative names
- GS-5885
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Biological description
Ledipasvir is an inhibitor of non-structural protein 5A of hepatitis C virus. It has potent effects against genotypes 1a, 1b, 4a, and 5a in vitro, but has lower activity against genotypes 2a and 3a. Ledipasvir can have additive to synergistic in vitro antiviral activity when combined with other agents.
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CAS Number
1256388-51-8 -
Chemical structure
Properties
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Chemical name
Methyl N-[(2S)-1-[(6S)-6-[5-[9,9-difluoro-7-[2-[(1S,2S,4R)-3-[(2S)-2-(methoxycarbonylamino)-3-methylbutanoyl]-3-azabicyclo[2.2.1]heptan-2-yl]-3H-benzimidazol-5-yl]fluoren-2-yl]-1H-imidazol-2-yl]-5-azaspiro[2.4]heptan-5-yl]-3-methyl-1-oxobutan-2-yl]carbamate
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Molecular weight
889.02 -
Molecular formula
C49H54F2N8O6 -
PubChem identifier
67505836 -
Storage instructions
Shipped at 4°C. Store at -20°C. -
Solubility overview
Soluble in ethanol to 25 mM and in DMSO to 10mM.
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SMILES
CC(C)C(C(=O)N1CC2(CC2)CC1C3=NC=C(N3)C4=CC5=C(C=C4)C6=C(C5(F)F)C=C(C=C6)C7=CC8=C(C=C7)N=C(N8)C9C1CCC(C1)N9C(=O)C(C(C)C)NC(=O)OC)NC(=O)OC -
Source
Synthetic
