LY 272015 hydrochloride, 5-HT2B antagonist (ab120546)
Key features and details
- Highly potent, selective 5-HT2B antagonist
- CAS Number: 172895-15-7
- Purity: > 99%
- Soluble in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
LY 272015 hydrochloride, 5-HT2B antagonist -
Description
Highly potent, selective 5-HT2B antagonist -
Biological description
Highly potent, selective 5-HT2B receptor antagonist (Ki values are 0.75, 21.63 and 28.7 nM for 5-HT2B, 5-HT2C and 5-HT2A receptors, respectively). Displays antihypertensive activity in vivo.
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Purity
> 99% -
CAS Number
172895-15-7 -
Chemical structure
Properties
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Chemical name
1-[(3,4-Dimethoxyphenyl)methy]-2,3,4,9-tetrahydro-6-methyl-1H-pyrido[3,4-b]indole hydrochloride -
Molecular weight
372.89 -
Molecular formula
C21H24N2O2.HCl -
PubChem identifier
9929423 -
Storage instructions
Store at +4°C. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
Cl.COc1ccc(cc1OC)CC3NCCc2c4cc(C)ccc4nc23 -
Source
Synthetic
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Research areas
