L-165,041, PPARdelta agonist (ab141126)
Key features and details
- Potent, selective PPARδ agonist
- CAS Number: 79558-09-1
- Purity: > 99%
- Soluble in 1eq. NaOH to 100 mM and in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
-
Product name
L-165,041, PPARdelta agonist -
Description
Potent, selective PPARδ agonist -
Biological description
Potent, selective PPARδ agonist (Ki values are 6 and 730 nM for PPARδ and PPARγ, respectively). Various pharmacological activities in vitro and in vivo including antiangiogenic and antiproliferative effects. Weak blood-brain barrier permeability.
-
Purity
> 99% -
CAS Number
79558-09-1 -
Chemical structure
Properties
-
Chemical name
2-[4-[3-(4-Acetyl-3-hydroxy-2-propylphenoxy)propoxy]phenoxy]acetic acid -
Molecular weight
402.44 -
Molecular formula
C22H26O7 -
PubChem identifier
6603901 -
Storage instructions
Store at -20°C. It is important to note that this product is reported to be light sensitive. Store In the Dark. Store under desiccating conditions. -
Solubility overview
Soluble in 1eq. NaOH to 100 mM and in DMSO to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
-
SMILES
Oc2c(ccc(OCCCOc1ccc(OCC(=O)O)cc1)c2CCC)C(C)=O -
Source
Synthetic
-
Research areas
- Signal Transduction
- Signaling Pathway
- Nuclear Signaling
- Nuclear Hormone Receptors
- Retinoic & Retinoid
- Signal Transduction
- Signaling Pathway
- Nuclear Signaling
- Nuclear Hormone Receptors
- Vitamin D Receptor
- Metabolism
- Pathways and Processes
- Metabolic signaling pathways
- Nucleotide metabolism
- Molecular processes
- Mitochondrial transcription
- Metabolism
- Pathways and Processes
- Metabolic signaling pathways
- Lipid and lipoprotein metabolism
- Lipid metabolism
- Metabolism
- Pathways and Processes
- Metabolic signaling pathways
- Lipid and lipoprotein metabolism
- Lipases
