KU-60019, ATM kinase inhibitor (ab144817)
Key features and details
- Potent, highly selective ATM kinase inhibitor
- CAS Number: 925701-49-1
- Purity: > 99%
- Soluble in ethanol to 100 mM and in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
KU-60019, ATM kinase inhibitor -
Description
Potent, highly selective ATM kinase inhibitor -
Biological description
Potent, highly selective ATM kinase inhibitor (IC50 = 6.3 nM). Inhibits migration and invasion of glioma cells. Shows similar target selectivity to KU-55933 (ab120637). Shows radiosensitizing effects in vivo. -
Purity
> 99% -
CAS Number
925701-49-1 -
Chemical structure
Properties
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Chemical name
2-((2S,6R)-2,6-Dimethylmorpholino)-N-(5-(6-morpholino-4-oxo-4H-pyran-2-yl)-9H-thioxanthen-2-yl)acetamide -
Molecular weight
547.67 -
Molecular formula
C30H33N3O5S -
PubChem identifier
15953870 -
Storage instructions
Store at -20°C (desiccating conditions). -
Solubility overview
Soluble in ethanol to 100 mM and in DMSO to 100 mM -
Handling
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SMILES
C[C@@H]1CN(C[C@@H](O1)C)CC(=O)NC2=CC3=C(C=C2)SC4=C(C=CC=C4C3)C5=CC(=O)C=C(O5)N6CCOCC6 -
Source
Synthetic
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Research areas
