Kenpaullone, CDK2, GSK3beta and LCK inhibitor (ab120937)
Key features and details
- CDK2, GSK3β and LCK inhibitor
- CAS Number: 142273-20-9
- Purity: > 98%
- Soluble in DMSO to 25 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Kenpaullone, CDK2, GSK3beta and LCK inhibitor -
Description
CDK2, GSK3β and LCK inhibitor -
Biological description
CDK2, GSK3β and LCK inhibitor (IC50 values are 0.67, 0.23 and 0.47 μM for CDK2, GSK3β and LCK, respectively). Antiproliferative activity in vitro. -
Purity
> 98% -
CAS Number
142273-20-9 -
Chemical structure
Properties
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Chemical name
9-Bromo-7,12-dihydroindolo[3,2-d][1]benzazepin-6(5H)-one -
Molecular weight
327.18 -
Molecular formula
C16H11BrN2O -
Storage instructions
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 25 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
O=C1Nc2ccccc2c2[nH]c3ccc(Br)cc3c2C1 -
Source
Synthetic
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Research areas
