JSH 23, NFkappaB transcriptional activity inhibitor (ab144824)
Key features and details
- NFκB transcriptional activity inhibitor
- CAS Number: 749886-87-1
- Purity: > 99%
- Soluble in ethanol to 75 mM and in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
JSH 23, NFkappaB transcriptional activity inhibitor -
Description
NFκB transcriptional activity inhibitor -
Biological description
NFκB transcriptional activity inhibitor (IC50 = 7.1 μM). Inhibits LPS-induced nuclear translocation of NFκB. Does not affect IκB degradation. Potentiates the antitumor effects of cisplatin (ab141398). Shows neuroprotective effects in vivo. -
Purity
> 99% -
CAS Number
749886-87-1 -
Chemical structure
Properties
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Chemical name
4-Methyl-1-N-(3-phenylpropyl)benzene-1,2-diamine -
Molecular weight
240.34 -
Molecular formula
C16H20N2 -
PubChem identifier
16760588 -
Storage instructions
Store at -20°C (desiccating conditions). -
Solubility overview
Soluble in ethanol to 75 mM and in DMSO to 100 mM -
Handling
Toxic, refer to SDS for further information.
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SMILES
CC1=CC(=C(C=C1)NCCCC2=CC=CC=C2)N -
Source
Synthetic
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Research areas