(E)-Capsaicin, Vanilloid receptor agonist (ab141000)
Key features and details
- Vanilloid receptor (VR1) agonist
- CAS Number: 404-86-4
- Purity: > 98%
- Soluble in DMSO to 50 mM and in ethanol to 50 mM
- Form / State: Solid
- Source: Capsicum sp.
Overview
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Product name
(E)-Capsaicin, Vanilloid receptor agonist -
Description
Vanilloid receptor (VR1) agonist -
Purity
> 98% -
CAS Number
404-86-4 -
Chemical structure
Properties
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Chemical name
(6E)-N-[(4-Hydroxy-3-methoxyphenyl)methyl]-8-methyl-6-nonenamide -
Molecular weight
305.42 -
Molecular formula
C18H27NO3 -
PubChem identifier
2548 -
Storage instructions
Store at +4°C. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 50 mM and in ethanol to 50 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
Oc1ccc(cc1OC)CNC(=O)CCCC/C=C/C(C)C -
Source
Capsicum sp.
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Research areas
Images
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Functional Studies - (E)-Capsaicin, Vanilloid receptor agonist (ab141000)Capsaicin induces Ca2+ influx via activation of TRPV1 channels expressed in C6 cells. Cells were loaded with Fluo-3 AM (ab145254) and stimulated with Capsaicin (ab141000). Changes in intracellular Ca2+ were detected via changes in Fluo-3 emission following application. The left panel shows normalized fluorescence before and after application (at 20 seconds) of 0-10 µM Capsaicin (as indicated). The right panel shows normalized fluorescence plotted against Capsaicin concentrations.