HC Toxin, histone deacetylase (HDAC) inhibitor (ab144531)
Key features and details
- Potent, cell-permeable histone deacetylase (HDAC) inhibitor
- CAS Number: 83209-65-8
- Purity: > 98%
- Soluble in DMSO
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
HC Toxin, histone deacetylase (HDAC) inhibitor -
Description
Potent, cell-permeable histone deacetylase (HDAC) inhibitor -
Biological description
Potent, cell-permeable histone deacetylase (HDAC) inhibitor. E. tenella HDAC (IC50 = 30 nM), Human HDAC 11 (IC50 = 430 nM). Induces apoptosis. Displays antiprotozoal and antitumorigenic activity. Active in vitro and in vivo. -
Purity
> 98% -
CAS Number
83209-65-8 -
Chemical structure
Properties
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Chemical name
(3S,6R,9S,12R)-6,9-Dimethyl-3-[6-[(2S)-oxiran-2-yl]-6-oxohexyl]-1,4,7,10-tetrazabicyclo[10.3.0]pentadecane-2,5,8,11-tetrone -
Molecular weight
436.50 -
Molecular formula
C21H32N4O6 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
O=C(CCCCC[C@@H]1NC(=O)[C@H]2CCCN2C(=O)[C@H](C)NC(=O)[C@@H](C)NC1=O)[C@@H]3CO3 -
Source
Synthetic
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Research areas
