Brevetoxin2 (PbTx-2), voltage-gated Na+ channel activator (ab143469)
Key features and details
- Potent allosteric voltage-gated Na+ channel activatior
- CAS Number: 79580-28-2
- Purity: > 95%
- Soluble in water and in ethanol
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Brevetoxin2 (PbTx-2), voltage-gated Na+ channel activator -
Description
Potent allosteric voltage-gated Na+ channel activatior -
Biological description
Potent allosteric voltage-gated Na+ channel activator. Binds to site 5 on NaV channels causing excessive influx of Na+. Inactivates nerve fibers in vivo. Induces an inflammatory response. Orally active. -
Purity
> 95% -
CAS Number
79580-28-2 -
Chemical structure
Properties
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Molecular weight
895.20 -
Molecular formula
C50H70O14 -
PubChem identifier
57369879 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water and in ethanol -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC1CC2C(CC3(C(O2)CC4C(O3)C(=CC(=O)O4)C)C)OC5C1OC6CC7C(CC8C(O7)(CC=CC9C(O8)CC1C(O9)CC2C(O1)(C(CC(O2)CC(=C)C=O)O)C)C)(OC6(CC5)C)C -
Source
Synthetic
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Research areas
