Ispinesib (SB-715992) (ab273521)
Key features and details
- Potent, selective and reversible allosteric inhibitor of KSP
- CAS Number: 336113-53-2
- Purity: > 98%
Soluble in DMSO to 50 mM and ethanol to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Ispinesib (SB-715992) -
Description
Potent, selective and reversible allosteric inhibitor of KSP -
Alternative names
- SB-715992
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Biological description
A potent, selective and reversible allosteric inhibitor of KSP with IC50 value of 0.5 nM. Often combines with chemotherapy drugs to tumor treatment.
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Purity
> 98% -
CAS Number
336113-53-2 -
Chemical structure
Properties
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Chemical name
N-(3-Aminopropyl)-N-[(1R)-1-[7-chloro-3,4-dihydro-4-oxo-3-(phenylmethyl)-2- quinazolinyl]-2-methylpropyl]-4-methylbenzamide
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Molecular weight
517.06 -
Molecular formula
C30H33ClN4O2 -
PubChem identifier
6851740 -
Storage instructions
Shipped at 4°C. Store at -20°C. -
Solubility overview
Soluble in DMSO to 50 mM and ethanol to 100 mM
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Handling
Refer to SDS for further information
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC1=CC=C(C=C1)C(=O)N(CCCN)[C@@H](C2=NC3=C(C=CC(=C3)Cl)C(=O)N2CC4=CC=CC=C4)C(C)C -
Source
Synthetic
Images
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Chemical Structure - Ispinesib (SB-715992) (ab273521)
Chemical structure of Ispinesib (SB-715992), 336113-53-2
