Isoimperatorin, COX-dependent PGD2 production inhibitor (ab143499)
Key features and details
- Inhibits COX-dependent PGD2 production
- CAS Number: 482-45-1
- Purity: > 98%
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Isoimperatorin, COX-dependent PGD2 production inhibitor -
Description
Inhibits COX-dependent PGD2 production -
Biological description
Inhibits COX-dependent PGD2 production (IC50 values are 11 and 24 μM for COX-1 and COX-2 respectively). Inhibits LTC4 production (IC50 = 6 μM). Shows antiproliferative effects. Shows vasodilatory and anti-inflammatory effects in vivo. Orally active. -
Purity
> 98% -
CAS Number
482-45-1 -
Chemical structure
Properties
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Chemical name
4-(3-Methylbut-2-enoxy)furo[3,2-g]chromen-7-one -
Molecular weight
270.28 -
Molecular formula
C16H14O4 -
PubChem identifier
68081 -
Storage instructions
Store at Room Temperature. The product can be stored for up to 12 months. -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC(=CCOC1=C2C=CC(=O)OC2=CC3=C1C=CO3)C -
Source
Synthetic
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Research areas