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Biochemicals

Isoimperatorin, COX-dependent PGD2 production inhibitor (ab143499)

Key features and details

  • Inhibits COX-dependent PGD2 production
  • CAS Number: 482-45-1
  • Purity: > 98%
  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    Isoimperatorin, COX-dependent PGD2 production inhibitor
  • Description

    Inhibits COX-dependent PGD2 production
  • Biological description

    Inhibits COX-dependent PGD2 production (IC50 values are 11 and 24 μM for COX-1 and COX-2 respectively). Inhibits LTC4 production (IC50 = 6 μM). Shows antiproliferative effects. Shows vasodilatory and anti-inflammatory effects in vivo. Orally active.
  • Purity

    > 98%
  • CAS Number

    482-45-1
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    4-(3-Methylbut-2-enoxy)furo[3,2-g]chromen-7-one
  • Molecular weight

    270.28
  • Molecular formula

    C16H14O4
  • PubChem identifier

    68081
  • Storage instructions

    Store at Room Temperature. The product can be stored for up to 12 months.
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CC(=CCOC1=C2C=CC(=O)OC2=CC3=C1C=CO3)C
  • Source

    Synthetic

  • Research areas

    • Biochemicals
    • Chemical Type
    • Biochemicals
    • Biochemicals
    • Pharmacology
    • Enzymes
    • Cyclooxygenase
    • Inhibitors
    • Biochemicals
    • Pharmacology
    • Signaling
    • Lipid signaling
    • Prostaglandins

Images

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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