Iodoacetamide, Alkylating agent (ab146212)
Key features and details
- Alkylating agent.
- CAS Number: 144-48-9
- Purity: > 98%
- Soluble in water to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Iodoacetamide, Alkylating agent -
Description
Alkylating agent. -
Alternative names
- 2-Iodoacetamide
- alpha-Iodoacetamide
- Monoiodoacetamide
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Biological description
Alkylating agent used in peptide mapping because it covalently binds with thiols in cysteine residues, thereby preventing disulfide bond formation. By virtue of reaction with cysteine, it is an irreversible inhibitor of enzymes with cysteine at the active site. Also reacts with histidine residues though much more slowly, and this activity is responsible for inhibition of ribonuclease.
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Purity
> 98% -
CAS Number
144-48-9 -
Chemical structure
Properties
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Chemical name
2-Iodoacetamide -
Molecular weight
184.96 -
Molecular formula
C2H4INO -
Storage instructions
Store at +4°C. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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Source
Synthetic
