Human ST2 Antibody Pair - BSA and Azide free (IL1RL1) (ab256737)
Key features and details
- Unconjugated capture and detector antibodies
- Adaptable to any antibody pair-based assay format
- Antibody concentration ~ 1 mg/ml
- BSA and azide free buffer - ready for conjugation
- Reacts with: Human, Monkey
Overview
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Product name
Human ST2 Antibody Pair - BSA and Azide free (IL1RL1)
See all ST2 kits -
Assay type
ELISA set -
Range
109.38 pg/ml - 7000 pg/ml -
Species reactivity
Reacts with: Human, Monkey -
Product overview
The Antibody Pair can be used to quantify Human ST2 (IL1RL1). BSA and Azide free antibody pairs include unconjugated capture and detector antibodies suitable for sandwich ELISAs. The antibodies are provided at an approximate concentration of 1 mg/ml as measured by the protein A280 method. The recommended antibody orientation is based on internal optimization for ELISA-based assays. Antibody orientation is assay dependent and needs to be optimized for each assay type. Both capture and detector antibodies are rabbit monoclonal antibodies delivering consistent, specific, and sensitive results.
For additional information on the performance of the antibody pair, see the equivalent SimpleStep ELISA® Kit (ab254505), which uses the same antibodies. However, due to differences in their formulation, this antibody pair cannot be used with the consumables provided with our SimpleStep ELISA Kits. Please note that the range provided for the pairs is only an estimation based on the performance of the related product using the same antibody pair. Performance of the antibody pair will depend on the specific characteristics of your assay. We guarantee the product works in sandwich ELISA, but we do not guarantee the sensitivity or dynamic range of the antibody pair in your assay.
Download SDS here.
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Tested applications
Suitable for: Sandwich ELISAmore details -
Platform
Reagents
Properties
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Storage instructions
Store at +4°C. Please refer to protocols. -
Carrier free
Yes -
Components 10 x 96 tests Human ST2 (IL1RL1) Capture Antibody (unconjugated) 1 x 100µg Human ST2 (IL1RL1) Detector Antibody (unconjugated) 1 x 100µg -
Research areas
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Function
Receptor for interleukin-33 (IL-33), its stimulation recruits MYD88, IRAK1, IRAK4, and TRAF6, followed by phosphorylation of MAPK3/ERK1 and/or MAPK1/ERK2, MAPK14, and MAPK8. Possibly involved in helper T-cell function. -
Tissue specificity
Highly expressed in kidney, lung, placenta, stomach, skeletal muscle, colon and small intestine. Isoform A is prevalently expressed in the lung, testis, placenta, stomach and colon. Isoform B is more abundant in the brain, kidney and the liver. Isoform C is not detected in brain, heart, liver, kidney and skeletal muscle. -
Sequence similarities
Belongs to the interleukin-1 receptor family.
Contains 3 Ig-like C2-type (immunoglobulin-like) domains.
Contains 1 TIR domain. -
Cellular localization
Secreted and Cell membrane. - Information by UniProt
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Alternative names
- DER-4
- DER4
- FIT 1
see all -
Database links
- Entrez Gene: 9173 Human
- Omim: 601203 Human
- SwissProt: Q01638 Human
- Unigene: 66 Human
Images
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Sandwich ELISA - Human ST2 Antibody Pair - BSA and Azide free (IL1RL1) (ab256737)To learn more about the advantages of recombinant antibodies see here.
