Human S100A12 ELISA Kit (ab213822)
Key features and details
- Sensitivity: 10 pg/ml
- Range: 31.2 pg/ml - 2000 pg/ml
- Sample type: Cell culture supernatant, Cell Lysate, EDTA Plasma, Hep Plasma, Serum
- Detection method: Colorimetric
- Assay type: Sandwich (quantitative)
- Reacts with: Human
Properties
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Storage instructions
Store at -20°C. Please refer to protocols. -
Components Identifier 1 x 96 tests ABC Diluent Buffer Blue Cap 1 x 12ml Adhesive Plate Seal 4 units Antibody Diluent Buffer Green Cap 1 x 12ml Anti-Human S100A12 coated Microplate (12 x 8 wells) 1 unit Avidin-Biotin-Peroxidase Complex (ABC) 1 x 100µl Biotinylated S100A12 Antibody 1 x 130µl Lyophilized recombinant human S100A12 standard 2 vials Sample Diluent Buffer Green Cap 1 x 30ml TMB Color Developing Agent Black Cap 1 x 10ml TMB Stop Solution Yellow Cap 1 x 10ml -
Research areas
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Function
Calcitermin possesses antifungal activity against C.albicans and is also active against E.coli and P.aeruginosa but not L.monocytogenes and S.aureus. Binds calcium, zinc and copper. Presence of zinc increases the affinity for calcium. Plays an important role in the inflammatory response. Interaction with AGER on endothelium, mononuclear phagocytes, and lymphocytes triggers cellular activation, with generation of key proinflammatory mediators. -
Tissue specificity
Monocytes and lymphocytes. -
Sequence similarities
Belongs to the S-101 family.
Contains 2 EF-hand domains. - Information by UniProt
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Alternative names
- CAAF1
- CAGC
- Calcitermin
see all -
Database links
- Entrez Gene: 6283 Human
- Omim: 603112 Human
- SwissProt: P80511 Human
- Unigene: 19413 Human
Images
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Human S100A12 ELISA Kit (ab213822) Standard Curve.
Human S100A12 ELISA Kit (ab213822) Standard Curve.