Human HCC-1 ELISA Kit (ab155433)
Key features and details
- Sensitivity: 7 pg/ml
- Range: 0.006 ng/ml - 1.5 ng/ml
- Sample type: Cell culture supernatant, Plasma, Serum
- Detection method: Colorimetric
- Assay type: Sandwich (quantitative)
- Reacts with: Human
Properties
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Storage instructions
Store at -20°C. Please refer to protocols. -
Components 1 x 96 tests 20X Wash Buffer Concentrate 1 x 25ml 400X HRP-Streptavidin Concentrate 1 x 200µl 5X Assay Diluent B 1 x 15ml Assay Diluent A 1 x 30ml Biotinylated anti-Human HCC-1 2 vials HCC-1 Microplate (12 x 8 wells) 1 unit Recombinant Human HCC-1 Standard (lyophilized) 2 vials Stop Solution 1 x 8ml TMB One-Step Substrate Reagent 1 x 12ml -
Research areas
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Relevance
Has weak activities on human monocytes and acts via receptors that also recognize MIP-1 alpha. It induced intracellular Ca2+ changes and enzyme release, but no chemotaxis, at concentrations of 100-1,000 nM, and was inactive on T-lymphocytes, neutrophils, and eosinophil leukocytes. Enhances the proliferation of CD34 myeloid progenitor cells. The processed form HCC-1(9-74) is a chemotactic factor that attracts monocytes eosinophils, and T-cells and is a ligand for CCR1, CCR3 and CCR5. -
Cellular localization
Secreted -
Alternative names
- C-C motif chemokine 14
- CC-1
- CC-3
see all -
Database links
- Entrez Gene: 6358 Human
- Omim: 601392 Human
- SwissProt: Q16627 Human
Images
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Typical Standard Curve
Representative standard curve using ab155433
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Typical Standard CurveRepresentative standard curve using ab155433