Astana Biomed Group, an authorized Abcam distributor in Central Asia

Human CCR7 knockout HeLa cell pellet (ab279153)

Overview

  • Product name

    Human CCR7 knockout HeLa cell pellet
    See all CCR7 kits

  • Product overview

    Abcam’s knockout cell pellets give you access to native proteins, without the need to culture cells. Our knockout cell pellets are prepared from our single-gene knockout cell lines and provide an additional offering to our cell lysates.

    Cells are snap-frozen to provide high quality pellets that are suitable for extraction with alternative lysis buffers or for preparation of lysates from subcellular fractions. Our knockout cell pellets are suitable for a variety of applications, including PCR, gene expression profiling and DNA library preparation.

  • Parental Cell Line

    HeLa

  • Organism

    Human

  • Mutation description

    Knockout achieved by using CRISPR/Cas9, 11 bp deletion in exon3 and 1 bp insertion in exon3.

  • Passage number

  • Knockout validation

    Sanger Sequencing

  • Notes

    Pellet size: 5 million cells/vial.

    This product is subject to limited use licenses from The Broad Institute, ERS Genomics Limited and Sigma-Aldrich Co. LLC, and is developed with patented technology. For full details of the licenses and patents please refer to our limited use license and patent pages.

Properties

Target

  • Function

    Receptor for the MIP-3-beta chemokine. Probable mediator of EBV effects on B-lymphocytes or of normal lymphocyte functions.

  • Tissue specificity

    Expressed in various lymphoid tissues and activated B- and T-lymphocytes, strongly up-regulated in B-cells infected with Epstein-Barr virus and T-cells infected with herpesvirus 6 or 7.

  • Sequence similarities

    Belongs to the G-protein coupled receptor 1 family.

  • Cellular localization

    Cell membrane.
  • Information by UniProt

  • Alternative names

    • BLR 2
    • BLR2
    • C C chemokine receptor type 7
    • C C CKR 7
    • C-C chemokine receptor type 7
    • C-C CKR-7
    • CC chemokine receptor 7
    • CC chemokine receptor type 7
    • CC CKR 7
    • CC-CKR-7
    • CCCKR7
    • CCR 7
    • CCR-7
    • Ccr7
    • CCR7_HUMAN
    • CD 197
    • CD197
    • CD197 antigen
    • CDw197
    • Chemokine (C C motif) receptor 7
    • Chemokine (C C) receptor 7
    • Chemokine C C motif receptor 7
    • Chemokine C C receptor 7
    • Chemokine receptor 7
    • Chemokine receptor 7-like protein
    • CMKBR7
    • EBI 1
    • EBI1
    • Ebi1h
    • EBV Induced G Protein Coupled Receptor 1
    • EBV-induced G-protein coupled receptor 1
    • Epstein Barr virus induced G protein coupled receptor
    • Epstein Barr virus induced gene 1
    • Epstein-Barr virus-induced G-protein coupled receptor 1
    • EVI 1
    • EVI1
    • Lymphocyte Specific G Protein Coupled Peptide Receptor
    • MGC108519
    • MIP 3 beta receptor
    • MIP-3 beta receptor
    • MIP3 Beta Receptor
    see all

Properties

Images

  • Sanger Sequencing - Human CCR7 knockout HeLa cell pellet (ab279153)
    Sanger Sequencing - Human CCR7 knockout HeLa cell pellet (ab279153)

    Allele-1: 11 bp deletion in exon3

     

  • Sanger Sequencing - Human CCR7 knockout HeLa cell pellet (ab279153)
    Sanger Sequencing - Human CCR7 knockout HeLa cell pellet (ab279153)

    Allele-2: 1 bp insertion in exon3

     

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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