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Signal Transduction Metabolism

Human Attractin Antibody Pair - BSA and Azide free (ab267708)

Human Attractin Antibody Pair - BSA and Azide free (ab267708)
  • ChIP - Anti-Histone H3 antibody - Nuclear Loading Control and ChIP Grade (ab1791)

Key features and details

  • Unconjugated capture and detector antibodies
  • Adaptable to any antibody pair-based assay format
  • Antibody concentration ~ 1 mg/ml
  • BSA and azide free buffer - ready for conjugation

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Overview

  • Product name

    Human Attractin Antibody Pair - BSA and Azide free
    See all Attractin kits
  • Assay type

    ELISA set
  • Range

    2.813 ng/ml - 180 ng/ml
  • Product overview

    The Antibody Pair can be used to quantify Human Attractin. BSA and Azide free antibody pairs include unconjugated capture and detector antibodies suitable for sandwich ELISAs. The antibodies are provided at an approximate concentration of 1 mg/ml as measured by the protein A280 method. The recommended antibody orientation is based on internal optimization for ELISA-based assays. Antibody orientation is assay dependent and needs to be optimized for each assay type. Both capture and detector antibodies are rabbit monoclonal antibodies delivering consistent, specific, and sensitive results.


    For additional information on the performance of the antibody pair, see the equivalent SimpleStep ELISA® Kit (ab263888), which uses the same antibodies. However, due to differences in their formulation, this antibody pair cannot be used with the consumables provided with our SimpleStep ELISA Kits. Please note that the range provided for the pairs is only an estimation based on the performance of the related product using the same antibody pair. Performance of the antibody pair will depend on the specific characteristics of your assay. We guarantee the product works in sandwich ELISA, but we do not guarantee the sensitivity or dynamic range of the antibody pair in your assay.


    Download SDS here.

  • Tested applications

    Suitable for: Sandwich ELISAmore details
  • Platform

    Reagents

Properties

  • Storage instructions

    Store at +4°C. Please refer to protocols.
  • Carrier free

    Yes
  • Components 10 x 96 tests
    Human Attractin Capture Antibody (unconjugated) 1 x 100µg
    Human Attractin Detector Antibody (unconjugated) 1 x 100µg
  • Research areas

    • Neuroscience
    • Neurology process
    • Metabolism
  • Function

    Involved in the initial immune cell clustering during inflammatory response and may regulate chemotactic activity of chemokines. May play a role in melanocortin signaling pathways that regulate energy homeostasis and hair color. Low-affinity receptor for agouti (By similarity). Has a critical role in normal myelination in the central nervous system.
  • Tissue specificity

    Isoform 2 is detected in plasma (at protein level). Expressed and secreted by activated T lymphocytes. Expressed at low to moderate levels in peripheral blood leukocytes, spleen, lymph node, tonsil, bone marrow and fetal liver. At very low levels found in thymus. Isoform 2 is the major isoform in peripheral blood leukocytes.
  • Sequence similarities

    Contains 1 C-type lectin domain.
    Contains 1 CUB domain.
    Contains 1 EGF-like domain.
    Contains 6 Kelch repeats.
    Contains 2 laminin EGF-like domains.
    Contains 4 PSI domains.
  • Post-translational
    modifications

    Heavily glycosylated.
  • Cellular localization

    Secreted and Cell membrane.
  • Target information above from: UniProt accession O75882 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt
  • Alternative names

    • ATRN
    • ATRN_HUMAN
    • Attractin
    • attractin 2
    • DPPT L
    • DPPT-L
    • KIAA0548
    • Mahogany homolog
    • mahogany protein
    • Mahogany, mouse, homolog of
    • MGCA
    see all

Images

  • Sandwich ELISA - Human Attractin Antibody Pair - BSA and Azide free (ab267708)
    Sandwich ELISA - Human Attractin Antibody Pair - BSA and Azide free (ab267708)
    To learn more about the advantages of recombinant antibodies see here.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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