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Signal Transduction Protein Phosphorylation Tyrosine Kinases Receptor Tyrosine Kinases

HNMPA-(AM)3, Insulin receptor tyrosine kinase inhibitor (ab141567)

Price and availability

93 811 ₸

Availability

Order now and get it on Thursday February 25, 2021

Key features and details

  • Insulin receptor tyrosine kinase inhibitor
  • CAS Number: 120944-03-8
  • Purity: > 98%
  • Soluble in ethanol to 25 mM and in DMSO to 25mM
  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    HNMPA-(AM)3, Insulin receptor tyrosine kinase inhibitor
  • Description

    Insulin receptor tyrosine kinase inhibitor
  • Biological description

    Insulin receptor tyrosine kinase inhibitor (IC50 = 100 μM). Inhibits serine and tyrosine autophosphorylation by the human insulin receptor. Cell-permeable analog of HNMPA (cell impermeable analog available ab141566).
  • Purity

    > 98%
  • General notes

    Product's appearance is colorless oil

  • CAS Number

    120944-03-8
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    P-[[(Acetyloxy)methoxy]-2-naphthalenylmethyl]-bis[(acetyloxy)methyl] ester phosphonic acid
  • Molecular weight

    454.36
  • Molecular formula

    C20H23O10P
  • PubChem identifier

    3619
  • Storage instructions

    Shipped at 4°C. Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in ethanol to 25 mM and in DMSO to 25mM
  • Handling

    Unstable; make up solutions fresh and use immediately.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CC(=O)OCOC(C1=CC2=CC=CC=C2C=C1)P(=O)(OCOC(=O)C)OCOC(=O)C
  • Source

    Synthetic

  • Research areas

    • Signal Transduction
    • Protein Phosphorylation
    • Tyrosine Kinases
    • Receptor Tyrosine Kinases
    • Biochemicals
    • Chemical Type
    • Biochemicals
    • Biochemicals
    • Pharmacology
    • Receptors & Transporters
    • Enzyme-Linked Receptors
    • Receptor tyrosine kinases
    • Insulin
    • Biochemicals
    • Pharmacology
    • Enzymes
    • Kinase
    • Tyrosine Kinase
    • Receptor Tyrosine Kinase
    • Insulin

Images

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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