HNHA, HDAC inhibitor (ab141262)
Key features and details
- Potent, cell-permeable HDAC inhibitor
- CAS Number: 926908-04-5
- Purity: > 98%
- Soluble in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
HNHA, HDAC inhibitor -
Description
Potent, cell-permeable HDAC inhibitor -
Alternative names
- Histone Deacetylase Inhibitor VI
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Biological description
Potent, cell-permeable HDAC inhibitor (IC50 = 100 nM). Induces histone hyperacetylation and p21 transcription with concomitant inhibition of cell cycle progression. Arrests cell cycle at G1/S phase in cancer cells. Antitumor and antiangiogenic agent. Active in vivo and in vitro.
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Purity
> 98% -
CAS Number
926908-04-5 -
Chemical structure
Properties
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Chemical name
N-Hydroxy-7-(2-naphthalenylthio)heptanamide -
Molecular weight
303.42 -
Molecular formula
C17H21NO2S -
PubChem identifier
16126782 -
Storage instructions
Store at -20°C. -
Solubility overview
Soluble in DMSO to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
ONC(=O)CCCCCCSc1ccc2ccccc2c1 -
Source
Synthetic
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Research areas
