H-89, PKA inhibitor (ab143787)
Key features and details
- Potent, cell-permeable PKA inhibitor
- CAS Number: 127243-85-0
- Purity: > 98%
- Soluble in water to 25 mM and DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
H-89, PKA inhibitor -
Description
Potent, cell-permeable PKA inhibitor -
Purity
> 98% -
CAS Number
127243-85-0 -
Chemical structure
Properties
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Chemical name
N-[2-[[(E)-3-(4-Bromophenyl)prop-2-enyl]amino]ethyl]isoquinoline-5-sulfonamide -
Molecular weight
446.36 -
Molecular formula
C20H20BrN3O2S -
PubChem identifier
449241 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water to 25 mM and DMSO to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Refer to SDS for further instructions.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
C1=CC2=C(C=CN=C2)C(=C1)S(=O)(=O)NCCNC/C=C/C3=CC=C(C=C3)Br -
Source
Synthetic
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Research areas
- Epigenetics and Nuclear Signaling
- DNA / RNA
- DNA Damage & Repair
- DNA Damage Response
- DNA Damage Recognition
- Metabolism
- Pathways and Processes
- Metabolic signaling pathways
- Lipid and lipoprotein metabolism
- Lipid metabolism
