GW542573X, KCa2 channel activator (ab120502)
Key features and details
- Novel, selective KCa2 channel activator
- CAS Number: 660846-41-3
- Purity: > 99%
- Supplied in ethanol (25 mg/ml)
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
GW542573X, KCa2 channel activator -
Description
Novel, selective KCa2 channel activator -
Biological description
Novel activator of KCa2 ('SK') channels. Selective SK1 channel activator (EC50 = 8.2 μM). First true activator of KCa2.x and KCa3.1 channels; displays 100-fold greater selectivity for KCa2.x over KCa3.1.
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Purity
> 99% -
General notes
Supplied in ethanol (25 mg/ml). Please note this compound is unstable as the solid form and unstable in DMSO
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CAS Number
660846-41-3 -
Chemical structure
Properties
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Chemical name
4-(2-Methoxyphenylcarbamoyloxymethyl)piperidine-1-carboxylic acid tert-butyl ester -
Molecular weight
364.44 -
Molecular formula
C19H28N2O5 -
PubChem identifier
24885053 -
Storage instructions
Store at +4°C (desiccating conditions). -
Solubility overview
Supplied in ethanol (25 mg/ml) -
Handling
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 6 months. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
COc2ccccc2NC(=O)OCC1CCN(CC1)C(=O)OC(C)(C)C -
Source
Synthetic
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Research areas
