Recombinant human EGFR (mutated T790 + C797 + L858) protein (Active) (ab223159)
Key features and details
- Expression system: Baculovirus infected Sf9 cells
- Purity: > 85% Densitometry
- Active: Yes
- Tags: GST tag N-Terminus
- Suitable for: Functional Studies, SDS-PAGE
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Product name
Recombinant human EGFR (mutated T790 + C797 + L858) protein (Active)
See all EGFR proteins and peptides -
Biological activity
The specific activity of ab223159 was determined to be 40 nmol/min/mg.
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Purity
> 85 % Densitometry. -
Expression system
Baculovirus infected Sf9 cells -
Accession
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Protein length
Protein fragment -
Animal free
No -
Nature
Recombinant -
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Species
Human -
Sequence
MRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKV LGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMA SVDNPHVCRLLGICLTSTVQLIMQLMPFGSLLDYVREHKDNIGSQYLLNW CVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGRAKLLGAEEK EYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDG IPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIE FSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYL IPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQ RYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNP APSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISL DNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA -
Amino acids
668 to 1210 -
Modifications
mutated T790 + C797 + L858 -
Tags
GST tag N-Terminus -
Additional sequence information
T790M C797S L858R (NM_005228).
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Preparation and Storage
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Stability and Storage
Shipped on Dry Ice. Upon delivery aliquot. Store at -80°C. Avoid freeze / thaw cycle.
pH: 7.50
Constituents: 0.79% Tris HCl, 0.88% Sodium chloride, 0.31% Glutathione, 0.003% EDTA, 0.004% DTT, 0.002% PMSF, 25% Glycerol (glycerin, glycerine)This product is an active protein and may elicit a biological response in vivo, handle with caution.
Images
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Functional Studies - Recombinant human EGFR (mutated T790 + C797 + L858) protein (Active) (ab223159)The specific activity of EGFR (ab223159) was determined to be 39 nmol/min/mg as per activity assay protocol
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SDS-PAGE - Recombinant human EGFR (mutated T790 + C797 + L858) protein (Active) (ab223159)SDS PAGE analysis of ab223159 -
SDS-PAGE - Recombinant human EGFR (mutated T790 + C797 + L858) protein (Active) (ab223159)SDS PAGE analysis of ab223159 -
SDS-PAGE - Recombinant human EGFR (mutated T790 + C797 + L858) protein (Active) (ab223159)SDS-PAGE analysis of ab223159.
MWt ~ 89-100 kDa.
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Functional Studies - Recombinant human EGFR (mutated T790 + C797 + L858) protein (Active) (ab223159)The specific activity of ab223159 in a kinase assay was determined to be 40 nmol/min/mg.
