GW 9662-d5, PPARgamma antagonist (ab141261)
Key features and details
- Potent, irreversible and selective PPARγ antagonist
- CAS Number:
- Purity: > 99%
- Soluble in ethanol to 25 mM and DMSO in 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
GW 9662-d5, PPARgamma antagonist -
Description
Potent, irreversible and selective PPARγ antagonist -
Biological description
Potent, irreversible and selective PPARγ antagonist (IC50 values are 3.3, 32 and 2000 nM at PPARγ, PPARα and PPARβ respectively). Anti-inflammatory and anticancer effects in vitro. Active in vivo.
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Purity
> 99% -
Chemical structure
Properties
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Chemical name
2-Chloro-5-nitro-N-(2,3,4,5,6-pentadeuterophenyl)benzamide -
Molecular weight
281.71 -
Molecular formula
C13H4ClD5N2O3 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in ethanol to 25 mM and DMSO in 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
O=C(Nc1c([2H])c([2H])c([2H])c([2H])c1[2H])c2cc(ccc2Cl)[N+]([O-])=O -
Source
Synthetic
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Research areas
