GBR 13069 dihydrochloride, dopamine reuptake inhibitor (ab146435)
Key features and details
- Potent dopamine reuptake inhibitor
- CAS Number: 67469-45-8
- Purity: > 99%
- Soluble in water to 5 mM and in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
GBR 13069 dihydrochloride, dopamine reuptake inhibitor -
Description
Potent dopamine reuptake inhibitor -
Biological description
Potent dopamine reuptake inhibitor (IC50 = 40 nM). Inhibits noradrenaline reuptake (IC50 = 800 nM). Stimulates locomotor activity and shows central effects in vivo.
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Purity
> 99% -
CAS Number
67469-45-8 -
Chemical structure
Properties
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Chemical name
1-[2-[Bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenyl-2-propen-1-yl)piperazine dihydrochloride -
Molecular weight
521.48 -
Molecular formula
C28H30F2N2O.2HCl -
Storage instructions
Store at Room Temperature. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water to 5 mM and in DMSO to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
c1ccc(cc1)/C=C/CN2CCN(CC2)CCOC(c3ccc(cc3)F)c4ccc(cc4)F.Cl.Cl -
Source
Synthetic
