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Galloflavin, Lactic acid dehydrogenase (LDH) inhibitor (ab141776)

Key features and details

  • Novel, non-competitive lactic acid dehydrogenase (LDH) inhibitor
  • CAS Number: 568-80-9
  • Purity: > 95%
  • Soluble in DMSO to 10 mM

  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    Galloflavin, Lactic acid dehydrogenase (LDH) inhibitor
  • Description

    Novel, non-competitive lactic acid dehydrogenase (LDH) inhibitor
  • Alternative names

    • NSC-107022
  • Biological description

    Novel, non-competitive lactic acid dehydrogenase (LDH) inhibitor (Ki values are 5.46 and 15.06 μM for LDH-A and LDH-B respectively). Non-competitive inhibition of pyruvate and NADH. Inhibits cell metabolism and induces cell death. Blocks RNA synthesis in vitro.

  • Purity

    > 95%
  • CAS Number

    568-80-9
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    6,8,9,10-Tetrahydroxypyrano[3,2-c][2]benzopyran-2,3-dione

  • Molecular weight

    278.17
  • Molecular formula

    C12H6O8
  • PubChem identifier

    54683147
  • Storage instructions

    Store at -20°C. It is important to note that this is air sensitive and impurities can occur as a result of air oxidation. It is important to note that this product is reported to be light sensitive. Store under desiccating conditions.
  • Solubility overview

    Soluble in DMSO to 10 mM

  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    C1=C2C(=C(C(=C1O)O)O)C3=C(C=C(C(=O)O3)O)OC2=O
  • Source

    Synthetic

Images

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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