Aminopterin, dihydrofolate reductase inhibitor (ab142394)
Key features and details
- Potent, competetive dihydrofolate reductase inhibitor
- CAS Number: 54-62-6
- Purity: > 98%
- Soluble in DMSO
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Aminopterin, dihydrofolate reductase inhibitor -
Description
Potent, competetive dihydrofolate reductase inhibitor -
Biological description
Potent, competitive dihydrofolate reductase inhibitor. Shows antineoplastic and immunosuppressive effects in vivo. Orally active. -
Purity
> 98% -
CAS Number
54-62-6 -
Chemical structure
Properties
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Chemical name
2-[[4-[(2,4-Diaminopteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid -
Molecular weight
440.41 -
Molecular formula
C19H20N8O5 -
PubChem identifier
2154 -
Storage instructions
Store at Room Temperature. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
C1=CC(=CC=C1C(=O)NC(CCC(=O)O)C(=O)O)NCC2=CN=C3C(=N2)C(=NC(=N3)N)N -
Source
Synthetic
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Research areas
