Galanthamine hydrobromide, Alkaloid acetylcholinesterase inhibitor (ab141114)
Key features and details
- Alkaloid acetylcholinesterase inhibitor
- CAS Number: 1953-04-4
- Purity: > 99%
- Soluble in water to 50 mM and in DMSO to 100 mM
- Form / State: Solid
Overview
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Product name
Galanthamine hydrobromide, Alkaloid acetylcholinesterase inhibitor -
Description
Alkaloid acetylcholinesterase inhibitor -
Alternative names
- Galantamine
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Biological description
Alkaloid acetylcholinesterase inhibitor (IC50 values are 0.85 and 12.1 μM for AChE and butyrylcholinesterase, respectively). Blood-brain barrier permeable. Active in vivo following oral administration. Prevents beta-amyloid induced apotosis. Reduces neurodegeneration in vivo.
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Purity
> 99% -
CAS Number
1953-04-4 -
Chemical structure
Properties
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Chemical name
(4aS,6R,8aS)-4a,5,9,10,11,12-Hexahydro-3-methoxy-11-methyl-6H-benzofuro[3a,3,2-ef][2]benzazepin-6-ol hydrobromide -
Molecular weight
368.27 -
Molecular formula
C17H21NO3.HBr -
PubChem identifier
121587 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water to 50 mM and in DMSO to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
Br.O[C@H]1C=C[C@@]42CCN(C)Cc3ccc(OC)c(O[C@H]2C1)c34 -
Research areas
