Dihydrotanshinone, cytotoxic agent (ab142423)
Key features and details
- Potent cytotoxic agent
- CAS Number: 87205-99-0
- Purity: > 90%
- Form / State: Solid
- Source: Salvia miltiorrhiza Bunge
Overview
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Product name
Dihydrotanshinone, cytotoxic agent -
Description
Potent cytotoxic agent -
Biological description
Potent cytotoxic agent (IC50 = 4.6 μM). Suppresses endothelial cell proliferation, migration, invasion and tube formation. Induces apoptosis of prostate cancer cells via induction of ER stress and/or inhibition of proteasome activity. Anti-angiogenic and antimicrobial agent. Active in vivo and in vitro. -
Purity
> 90% -
CAS Number
87205-99-0 -
Chemical structure
Properties
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Chemical name
(1R)-1,6-Dimethyl-1,2-dihydronaphtho[1,2-g][1]benzofuran-10,11-dione -
Molecular weight
278.30 -
Molecular formula
C18H14O3 -
PubChem identifier
11425923 -
Storage instructions
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC1COC2=C1C(=O)C(=O)C3=C2C=CC4=C3C=CC=C4C -
Source
Salvia miltiorrhiza Bunge
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Research areas
